Collection: Products for Dry Mouth

Dry mouth can make everyday things—talking, eating, sleeping, or simply feeling comfortable—harder than they should be. It can happen for many reasons, including medications, stress, diet, dehydration, certain health conditions, and cancer treatment.
Our products for dry mouth offer thoughtful options for both daily care and targeted comfort. From hydrating toothpaste and rinses to an easy-to-carry mist and soothing dental gel, each one is designed to fit naturally into your routine.

Collection: Products for Dry Mouth

A unique science-backed approach to oral care

★★★★★
Thousands of 5 Star Reviews
★★★★★

Total health is important to me, so PerioSciences is the only toothpaste and mouth rinse I put into my body.

- Erin J.
Austin, TX
★★★★★

HALLELUJAH. PerioSciences is the only product I’ve found that works! No more sensitivity and the canker sores are gone! I’m so thankful!

- Kathy H.
Fredericksburg, TX
★★★★★

Great product! Alcohol free and a great taste. It doesn’t burn your mouth like other mouth rinses.

- Kristin S.
Oklahoma City, OK
★★★★★

Who knew antioxidants were also important for your teeth. This White Care toothpaste really helped get rid of the discoloration on my teeth caused by coffee.

- Chidi Y.
San Jose, CA
★★★★★

I got the gel to use after I had teeth pulled. My gums felt great and it was very soothing. You definitely can’t go wrong using this.

- Becca G.
McAllen, TX
★★★★★

The Sensitive toothpaste is much better than Sensodine. The taste is pleasant and the paste is not chalky.A tube lasts a long time.

- Javier R.
Seattle, WA
★★★★★

Excellent products! They were recommended by my dentist.

- Brittany C.
Bainbridge, WA
★★★★★

The PerioSciences Sensitive Oral Care System actually improved the overall condition of my gums and sensitivity. I’ve been a faithful user twice a day and it offers rouond-the-clock relief.

- Kris F.
Santa Monica, CA

Why Dentists Trust PerioSciences

With so many oral care options available, it helps to know what dental professionals actually stand behind.

In this video, Dr. Yazzi shares why our antioxidant-powered formulas are designed to support gum health, comfort, and long-term wellness — without harsh ingredients or unnecessary fillers.

Thoughtfully formulated. Professionally trusted.

What Makes Moisyn® and AO ProVantage Different

Moisyn® is designed to do more than briefly wet the mouth. Its pH-balanced, alcohol-free formula helps attract and hold moisture, creating comfortable lubrication with a more natural, saliva-like feel. Clinical performance data support moisturizing and lubricating relief for up to six hours.

AO ProVantage Gel takes a more targeted approach. Its concentrated antioxidant formula, made with Phloretin and Ferulic Acid, is applied directly to the gums and other oral tissues to soothe areas that feel dry or uncomfortable. Choose the Standard size for home or the compact On-the-Go size to keep nearby.


Build a Dry Mouth Routine That Works for You

Dry mouth doesn’t always feel the same from morning to night, so your routine should flex with it. Start with Hydrating Toothpaste for everyday brushing, then use Moisyn® Oral Rinse or Hydrating Mouthwash as directed. Apply AO ProVantage Gel morning and evening after brushing for focused care, and keep Moisyn® Oral Mist nearby for as-needed comfort throughout the day.

You don’t need every product to get started. Choose the combination that best fits when and where you notice dryness.


Frequently Asked Questions

Why is my mouth dry all the time?

Dry mouth can have many causes. Common ones include medication side effects, dehydration, stress, certain health conditions, and cancer treatments that affect saliva production. Dry mouth is not simply a normal part of getting older.
If your dryness is new, persistent, or getting worse, talk with your dentist or doctor. They can help you understand what may be causing it and recommend the right next step.

Which PerioSciences dry mouth product is right for me?

Many customers combine daily and on-the-go products to create a routine that works from morning to night.
Hydrating Toothpaste is an easy place to begin for everyday brushing. Moisyn® Oral Rinse and Hydrating Mouthwash add moisture and comfort to your daily routine, while Moisyn® Oral Mist offers convenient refreshment whenever you need it.
For more focused care, AO ProVantage Gel can be applied directly to the gums and other oral tissues––available in two sizes.

Are these dry mouth products clinically proven to help?

Moisyn® has been clinically studied for dry mouth comfort. Clinical performance data support moisturizing and lubricating relief for up to six hours.
The other products in this collection are thoughtfully formulated with ingredients selected to support a more comfortable dry mouth routine. Visit the individual product pages for specific ingredients, benefits, and directions.

How long does the relief actually last?

Patients have reported up to 6 hours of relief. Use Moisyn® Oral Rinse and Moisyn® Oral Mist together throughout the day for optimal comfort.

Can I use these dry mouth products together?

Absolutely. They can be used as complementary parts of your routine and are actually more effective when paired. Brush with Hydrating Toothpaste, then use Moisyn® Oral Rinse or Hydrating Mouthwash as directed. Apply AO ProVantage Gel after brushing for focused care, and use Moisyn® Oral Mist whenever you want added refreshment throughout the day.
Always follow the directions provided with each product.

Is there a toothpaste for dry mouth I can use at night?

Yes. Hydrating Toothpaste gently cleans without commonly used harsh ingredients, while leaving your mouth feeling hydrated, making it a comfortable choice for twice-daily brushing—especially before bed.

Can I use these dry mouth products with my medications?

Because medications and individual health needs vary, check with your dentist, doctor, or pharmacist if you’re unsure whether a product is right for you. Do not stop or change a prescription because it causes dry mouth without first speaking with your prescriber.
Please note that Moisyn® contains shellfish derivatives, so review its allergen information before use.

Do you offer a sample kit I can try first?

While we don’t offer sample kits, our On-the-Go AO ProVantage Gel comes in a compact, travel-friendly size, making it an easy way to try our antioxidant formula.