Collection: Mouth Rinse

Freshen your breath and maintain bright and healthy smiles with our mouth rinses. The result of over a decade of world-class research, each one is specially formulated to target dental care issues and includes novel, natural ingredients that possess antioxidant properties. What’s more, they’re free of alcohol, harsh chemicals, and unnecessary dyes. Find the one that’s perfect for you.

Collection: Mouth Rinse

A unique science-backed approach to oral care

Why PerioSciences?

We understand you may have reservations about trying a mouth rinse or toothpaste by a brand unfamiliar to you, especially if you are experiencing oral health issues and are searching for fast, effective relief.

At PerioSciences, we have worked with the dentist community for over a decade and conducted cutting-edge research to develop such products. Proof of that lies in the fact that our toothpaste for sensitive teeth has been clinically proven to provide sensitivity relief within 72 hours. That’s why many of our products aren’t just recommended by dentists, but used by them as well.

What’s more, we’ve received thousands of 5-star ratings from our customers, old and new. Visit our reviews to learn more. And if you’re keen to find out which dental care product is ideal for addressing your oral health concerns, then take our quiz based on the questions dentists ask during consultations.

Our unique approach to mouth rinses

For more than a decade we’ve been working with the dentist community to develop a novel, natural approach to oral care. Our specially formulated toothpastes and mouthwashes are the result of that – harnessing the power of natural ingredients known for their powerful antioxidant and antibacterial properties. Learn more about our antioxidant mouthwashes, and which one may be right for you, below.

Take It From The Pros

  • Dr. M. Crofcheck

    "I conduct many periodontal procedures each year. I recommend the PerioSciences products to all my patients as an important component of their home care regimen."

    - Dr. M. Crofcheck


    Houston, TX

  • Dr. S. John

    "Our post-op patients need time to heal and a good after care regimen. When they use AO ProVantage, their soft tissues instantly feel soothed/quickly feel much better."

    - Dr. S. John


    San Mateo, CA

  • Dr. J. Kim

    "The use of antioxidants to enhance and accelerate healing immediately after surgery is a new standard of care."

    - Dr. J. Kim


    Diamond Bar, CA

  • quote

    "I have recommended the AO Gel to my post-surgical patients for more than 5 years. Patients love the refreshing soothing effects when they use it as part of their home care/after care oral hygiene regimen."

    - Dr. E. Allen


    Dallas, TX

  • quote

    "PerioSciences is a part of my patients post-surgical protocol. All patients, even the healthiest ones, benefit from the soothing properties of PerioSciences gel, no matter what the condition."

    - Dr. D. Yu


    Austin, TX

  • quote

    "Topically applied antioxidants in AO ProVantage gel are known for their anti-inflammatory effects.* It is my go-to recommendation to support patient's healing after all periodontal procedures." *shown in laboratory studies

    - Dr. S. Low


    Gainesville, FL


+ Does your mouth rinse contain alcohol?
+ How do I use your mouth rinse?

We recommend you use one teaspoon daily after brushing your teeth. Swish the mouth rinse between your teeth and around the soft tissue in your mouth for 30 to 60 seconds. Also tilt your head back and gargle, but do not swallow. Spit, and refrain from eating and drinking for the next 30 minutes.

+ How long do I need to use your mouth rinse before I see results?

Our antioxidant mouthwashes are formulated to help when used on a daily basis. For best results, we recommend using the Oral Care System designed to target your specific oral health issue. For example, if you are experiencing sensitivity, consider using our Oral Care System For Sensitive Teeth. It includes our toothpaste for sensitivity, which is clinically proven to provide relief within 72 hours.