Premium Skincare Made For Your Mouth

From The Co-Founder And Former Co-CEO of SkinCeuticals®

Customer Favorites

Dental Gel

30 ml

$43.00

Whitening Toothpaste

3 oz

$19.50

Natural Toothpaste

3 oz

$19.50

AO ProToothpaste - Sensitive

AO ProToothpaste - Sensitive

3.0 oz

$19.50

People Are Talking

Choose Your Smile Care

No fluoride, no alcohol, no sodium lauryl sulfate. Shop now

Natural

Brighten teeth & soothe aggravated tissue post bleaching. Shop now

Whitening

Soothe the feeling of dryness in the mouth. Shop now

Hydrating

Made with potassium nitrate to soothe oral sensitivity and freshen breath. Shop now

Sensitive

What Makes Us Different Makes All the Difference

We are the ONLY patented Antioxidant Smile Care Formula

Ludicrous amounts of antioxidants!

Formulated with our unique blend of antioxidants phloretin and ferulic acid, our products deliver a full-mouth refresh and contribute to the overall health of your whole mouth.

Dental professional approved.

Our products are endorsed and used by thousands of dental professionals.

Backed by Science.

Decades of research and a patent to prove it.

Thousands of
5 Star Reviews

  • Total health is important to me, so PerioSciences is the only toothpaste and mouth rinse I put into my body.

    - Erin J.

    Austin, TX

  • HALLELUJAH. PerioSciences is the only product I’ve found that works! No more sensitivity and the canker sores are gone! I’m so thankful!

    - Kathy H.

    Fredericksburg, TX

  • Great product! Alcohol free and a great taste. It doesn’t burn your mouth like other mouth rinses.

    - Kristin S.

    Oklahoma City, OK

  • Who knew antioxidants were also important for your teeth. This White Care toothpaste really helped get rid of the discoloration on my teeth caused by coffee.

    - Chidi Y.

    San Jose, CA

  • I got the gel to use after I had teeth pulled. My gums felt great and it was very soothing. You definitely can’t go wrong using this.

    - Becca G.

    McAllen, TX

  • The PerioSciences Sensitive Oral Care System actually improved the overall condition of my gums and sensitivity. I’ve been a faithful user twice a day and it offers rouond-the-clock relief.

    - Kris F.

    Santa Monica, CA

  • The Sensitive toothpaste is much better than Sensodine. The taste is pleasant and the paste is not chalky.
    A tube lasts a long time.

    - Javier R.

    Seattle, WA

  • Excellent products! They were recommended by my dentist.

    - Brittany C.

    Bainbridge, WA

Take It From The Pros

  • "I conduct many periodontal procedures each year. I recommend the PerioSciences products to all my patients as an important component of their home care regimen."

    - Dr. M. Crofcheck

    Periodontist

    Houston, TX

  • "Our post-op patients need time to heal and a good after care regimen. When they use AO ProVantage, their soft tissues instantly feel soothed/quickly feel much better."

    - Dr. S. John

    Periodontist

    San Mateo, CA

  • "The use of antioxidants to enhance and accelerate healing immediately after surgery is a new standard of care."

    - Dr. J. Kim

    Periodontist

    Diamond Bar, CA

  • "I have recommended the AO Gel to my post-surgical patients for more than 5 years. Patients love the refreshing soothing effects when they use it as part of their home care/after care oral hygiene regimen."

    - Dr. E. Allen

    Periodontist

    Dallas, TX

  • "PerioSciences is a part of my patients post-surgical protocol. All patients, even the healthiest ones, benefit from the soothing properties of PerioSciences gel, no matter what the condition."

    - Dr. D. Yu

    Periodontist

    Austin, TX

  • "Topically applied antioxidants in AO ProVantage gel are known for their anti-inflammatory effects.* It is my go-to recommendation to support patient's healing after all periodontal procedures." *shown in laboratory studies

    - Dr. S. Low

    Periodontist

    Gainesville, FL