★★★★★
Thousands of 5 Star Reviews
★★★★★

Total health is important to me, so PerioSciences is the only toothpaste and mouth rinse I put into my body.

- Erin J.
Austin, TX
★★★★★

HALLELUJAH. PerioSciences is the only product I’ve found that works! No more sensitivity and the canker sores are gone! I’m so thankful!

- Kathy H.
Fredericksburg, TX
★★★★★

Great product! Alcohol free and a great taste. It doesn’t burn your mouth like other mouth rinses.

- Kristin S.
Oklahoma City, OK
★★★★★

Who knew antioxidants were also important for your teeth. This White Care toothpaste really helped get rid of the discoloration on my teeth caused by coffee.

- Chidi Y.
San Jose, CA
★★★★★

I got the gel to use after I had teeth pulled. My gums felt great and it was very soothing. You definitely can’t go wrong using this.

- Becca G.
McAllen, TX
★★★★★

The Sensitive toothpaste is much better than Sensodine. The taste is pleasant and the paste is not chalky.A tube lasts a long time.

- Javier R.
Seattle, WA
★★★★★

Excellent products! They were recommended by my dentist.

- Brittany C.
Bainbridge, WA
★★★★★

The PerioSciences Sensitive Oral Care System actually improved the overall condition of my gums and sensitivity. I’ve been a faithful user twice a day and it offers rouond-the-clock relief.

- Kris F.
Santa Monica, CA

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Why Dentists Trust PerioSciences

With so many oral care options available, it helps to know what dental professionals actually stand behind.

In this video, Dr. Yazzi shares why our antioxidant-powered formulas are designed to support gum health, comfort, and long-term wellness — without harsh ingredients or unnecessary fillers.

Thoughtfully formulated. Professionally trusted.

Cavity Prevention Toothpaste

Nobody wants a cavity. Especially since the only treatment for a cavity is a filling. That’s why the best approach to tooth decay is prevention and protection.

Our antioxidant toothpastes do just that. Each one has been developed to tackle a specific dental concern, including hydration, post-whitening, and sensitivity (which is clinically proven to provide consistent relief within 72 hours).

They’re all specially formulated and contain a unique blend of the following three ingredients:

  • Fluoride: a naturally occurring mineral that has been scientifically proven to combat tooth decay and help teeth resist bacteria.
  • Nano-Hydroxyapatite: another naturally occurring mineral that helps teeth fight decay and the development of cavities.
  • Phloretin and Ferulic Acid: naturally occurring antioxidants that neutralize free radicals that could damage your oral tissues - to ensure your teeth and gums stay healthy.

These ingredients work together to protect your teeth from decay. What’s more, according to a study published in the Journal of Dental Research, Fluoride and Nano-Hydroxyapatite are considered to be incredibly effective when paired together in promoting the remineralization and strengthening of teeth.

For best results, pair our antioxidant toothpastes with our antioxidant mouth rinses, or try our Oral Care Systems.

From our Blog

  1. What Does A Cavity Look Like? (And Does It Hurt?)

Frequently Asked Questions

What causes cavities?

Cavities can be formed by a combination of factors including but not limited to: poor oral hygiene; the build-up of plaque, which is a sticky film where bacteria breed; a diet high in sugars and foods that harm enamel; and dry mouth.

What do cavities look like?

A cavity is a hole in your tooth. This hole isn't always easy to identify, but if you see discoloration or a brown or black spot, it's likely to be a cavity. We cover this in greater detail, along with other signs that may indicate you have a cavity, in our post on what does a cavity look like?

How do I get rid of a cavity?

Despite the internet touting many natural home remedies, there really is only one way to get rid of a cavity, and that's by going to the dentist to get a filling.

How do I avoid or prevent cavities?

Practicing good oral hygiene is key to cavity-prevention. You should floss and brush your teeth twice daily after meals. Limit the amount of sugary foods and drinks that you consume. And make sure you visit your dentist at least once a year for a check-up. Products for cavities that contain fluoride can also be used to support your teeth.

What is the active ingredient in toothpaste that prevents cavities?

Fluoride is the most common and effective ingredient in toothpaste for preventing cavities. It has been scientifically proven to help strengthen tooth enamel and make it more resistant to decay caused by acids from plaque bacteria. Our toothpaste for sensitive teeth, hydrating toothpaste, and post-whitening toothpaste contain the highest amount of fluoride permitted in over-the-counter toothpastes.

Can I reverse small cavities with these products?

Unfortunately, no. When it comes to cavities, prevention is the best defense. You cannot reverse a cavity or hole in the tooth that requires a filling. However, these products are formulated to reverse early-stage enamel damage - often visible as "white spots" - by intensely supporting the natural remineralization process.

What are the key ingredients in your oral care products for cavity-prevention?

Our cavity prevention approach is based on a dual-action system that is scientifically proven to be highly effective in promoting remineralization. These antioxidant toothpastes carry the maximum over-the-counter amount of Fluoride, a scientifically proven mineral that remineralizes enamel and actively strengthens the tooth structure to make it highly resistant to acid and bacteria. The toothpastes also carry Nano-Hydroxyapatite, a naturally occurring calcium mineral that works on a microscopic level to fill in enamel micro-cracks and helps repair the early signs of cavities and erosion.