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★★★★★
Thousands of 5 Star Reviews
★★★★★

Total health is important to me, so PerioSciences is the only toothpaste and mouth rinse I put into my body.

- Erin J.
Austin, TX
★★★★★

HALLELUJAH. PerioSciences is the only product I’ve found that works! No more sensitivity and the canker sores are gone! I’m so thankful!

- Kathy H.
Fredericksburg, TX
★★★★★

Great product! Alcohol free and a great taste. It doesn’t burn your mouth like other mouth rinses.

- Kristin S.
Oklahoma City, OK
★★★★★

Who knew antioxidants were also important for your teeth. This White Care toothpaste really helped get rid of the discoloration on my teeth caused by coffee.

- Chidi Y.
San Jose, CA
★★★★★

I got the gel to use after I had teeth pulled. My gums felt great and it was very soothing. You definitely can’t go wrong using this.

- Becca G.
McAllen, TX
★★★★★

The Sensitive toothpaste is much better than Sensodine. The taste is pleasant and the paste is not chalky.A tube lasts a long time.

- Javier R.
Seattle, WA
★★★★★

Excellent products! They were recommended by my dentist.

- Brittany C.
Bainbridge, WA
★★★★★

The PerioSciences Sensitive Oral Care System actually improved the overall condition of my gums and sensitivity. I’ve been a faithful user twice a day and it offers rouond-the-clock relief.

- Kris F.
Santa Monica, CA

Why Dentists Trust PerioSciences

Watch Video

With so many oral care options available, it helps to know what dental professionals actually stand behind.

In this video, Dr. Yazzi shares why our antioxidant-powered formulas are designed to support gum health, comfort, and long-term wellness — without harsh ingredients or unnecessary fillers.

Thoughtfully formulated. Professionally trusted.

Which Oral Care System Is Right For You?

Our 3-product Oral Care Systems are the result of extensive research and coordination with dental professionals. They include antioxidant toothpaste, mouthwash, and dental gel. Designed to be used twice daily, these products work synergistically to deliver a full-mouth refresh while contributing to the overall health of your mouth.

Our Natural Oral Care System is Fluoride-free and contains no harsh chemicals. The toothpaste is specially formulated with natural ingredients known for their antioxidant properties and gently yet effectively cleans your teeth, while the mouthwash is alcohol-free and sugar-free to give you long-lasting fresh breath. The dental gel soothes and supports soft oral tissues.

Our Whitening Oral Care System is ideal for those who whiten their teeth using peroxide-based treatments. While such treatments are effective at whitening your teeth, they can also irritate your gums and cause discomfort or pain. The products in this system work to maximize the effects of your teeth-whitening treatment while nourishing oral tissues to reduce feelings of irritation. The result is a longer-lasting, brighter smile!

Our Oral Care System For Sensitive Teeth has been developed to help you eat, drink, and do the things you love without feelings of discomfort. The Toothpaste For Sensitive Teeth has the maximum permitted level of Fluoride and Potassium Nitrate in an over-the-counter toothpaste to protect your teeth. What’s more, it was clinically proven to reduce feelings of sensitivity within 72 hours.

Our Hydrating Oral Care System is for those looking for an extra dose of hydration in their mouth. The carefully selected natural ingredients work to moisturize the oral cavity and support moisture retention, to keep you feeling refreshed.

From our Blog

  1. Harnessing the Power of Antioxidants for Optimal Oral Health
  2. Why Are My Teeth Sensitive?
    Ericka Simancas Mar 17, 2026

    Why Are My Teeth Sensitive?

    Do you feel pain or discomfort when eating ice cream or drinking a hot coffee? This can be a sign of an underlying dental problem like a cavity or it may just be that you have sensitive teeth.

  3. Salt Mouth Rinse Benefits
    Mackenzie Blinn Mar 17, 2026

    Salt Mouth Rinse Benefits

    While many people only consider using a mouth rinse as a way to freshen the breath, these products offer a lot more benefits. Together with brushing and flossing, mouth rinses ensure good oral hygiene and reduce the chances of gum disease, tartar, plaque and many other problems linked with poor oral health.

  4. Foods That Strengthen Teeth (And Foods To Avoid)

Frequently Asked Questions

+ What does PerioSciences’ Oral Care System do?

There are four Oral Care Systems - Natural, Whitening, Hydrating, and Sensitive. Each one has been specially formulated to address a specific dental concern. They each include care products like antioxidant toothpaste, mouthwash, and dental gel that work together to target the dental concern while keeping your teeth clean, your gums healthy, and your breath fresh.

+ How do I use PerioSciences’ Oral Care System?

We recommend you use the products in your Oral Care System twice daily. First, brush your teeth with the toothpaste. Second, rinse your mouth with 1 tsp of the mouthwash for up to 1 minute and then spit out the mouthwash. Do not swallow the mouthwash. Third, apply a pea-sized amount of the dental gel to your gums using a fingertip or cotton swab. Let the gel dissolve, and spit out any excess. Do not eat or drink for 30 minutes after applying the gel.

Which oral care system is right for me?

Each is designed for specific needs. Take a look at the comparison table we have provided just below the products, or try our Smile Care Quiz to find the perfect match based on your oral care concerns - like dryness, sensitivity, or whitening aftercare.

What’s the correct order to use the three products in the system?

We recommend the following steps.

  1. Brush your teeth with the antioxidant toothpaste.
  2. Rinse with 1 tsp of mouth rinse for up to 1 minute, then spit out the excess.
  3. Apply a pea-sized amount of the dental gel to your upper and lower gums using a fingertip or cotton swab. Let the gel dissolve. Do not drink or eat anything for 30 minutes thereafter.
Are these oral care products Fluoride-free?

The Natural Oral Care System is the only system with Fluoride-free toothpaste. The others feature Fluoride and Nano-Hyroxyapatite formulations.

How long do these oral care products typically last with daily use?

Each system should last 60 days when used twice daily.

Are these oral care products safe for kids, older adults, or people with health sensitivities?

Yes, they are free from harsh chemicals and alcohol. However, always consult with your dentist for use with young children or those with medical conditions.