★★★★★
Thousands of 5 Star Reviews
★★★★★

Total health is important to me, so PerioSciences is the only toothpaste and mouth rinse I put into my body.

- Erin J.
Austin, TX
★★★★★

HALLELUJAH. PerioSciences is the only product I’ve found that works! No more sensitivity and the canker sores are gone! I’m so thankful!

- Kathy H.
Fredericksburg, TX
★★★★★

Great product! Alcohol free and a great taste. It doesn’t burn your mouth like other mouth rinses.

- Kristin S.
Oklahoma City, OK
★★★★★

Who knew antioxidants were also important for your teeth. This White Care toothpaste really helped get rid of the discoloration on my teeth caused by coffee.

- Chidi Y.
San Jose, CA
★★★★★

I got the gel to use after I had teeth pulled. My gums felt great and it was very soothing. You definitely can’t go wrong using this.

- Becca G.
McAllen, TX
★★★★★

The Sensitive toothpaste is much better than Sensodine. The taste is pleasant and the paste is not chalky.A tube lasts a long time.

- Javier R.
Seattle, WA
★★★★★

Excellent products! They were recommended by my dentist.

- Brittany C.
Bainbridge, WA
★★★★★

The PerioSciences Sensitive Oral Care System actually improved the overall condition of my gums and sensitivity. I’ve been a faithful user twice a day and it offers rouond-the-clock relief.

- Kris F.
Santa Monica, CA

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Why Dentists Trust PerioSciences

With so many oral care options available, it helps to know what dental professionals actually stand behind.

In this video, Dr. Yazzi shares why our antioxidant-powered formulas are designed to support gum health, comfort, and long-term wellness — without harsh ingredients or unnecessary fillers.

Thoughtfully formulated. Professionally trusted.

What does PerioSciences AO ProVantage Dental Gel do?

Our dental gel is the result of years of research and consultation with the dentist community. It contains a patented blend of natural ingredients known for their antioxidant properties (the AO stands for antioxidant), and is designed to take your oral care to the next level. Cool and minty, it freshens your breath while helping to reduce feelings of oral sensitivity or discomfort caused by:

  • braces
  • dental implants
  • dental surgery
  • dry mouth
  • mouth burn (such as when you eat food that scalds the roof of your mouth)
  • tooth whitening procedures

It also promotes an improved appearance of your gums. Choose between our travel-friendly, On-The-Go AO ProVantage Dental Gel and our full-sized AO ProVantage Dental Gel. Subscribe to enjoy a 15% discount on all future orders.

From our Blog

  1. Harnessing the Power of Antioxidants for Optimal Oral Health
  2. Why Is My Mouth So Dry When I Wake Up?
    Ericka Simancas Mar 03, 2026

    Why Is My Mouth So Dry When I Wake Up?

    Next to waking up with a numb arm, waking up with a bone dry mouth in the morning can be one of the worst ways to start your day. For some people some simple changes in habit can help prevent dry mouth in the morning, but for others the issue may be more serious. If you are concerned that you’re consistently waking up in the morning with this condition, please contact your doctor immediately.

  3. Why Are My Teeth Sensitive?
    Ericka Simancas Nov 25, 2024

    Why Are My Teeth Sensitive?

    Do you feel pain or discomfort when eating ice cream or drinking a hot coffee? This can be a sign of an underlying dental problem like a cavity or it may just be that you have sensitive teeth.

Frequently Asked Questions

+ What is dental gel?

Dental gel is designed to provide relief from feelings of discomfort or irritation in your mouth. It should be applied to your mouth’s soft tissues (that is, to the lips, gums, palate, and the insides of your cheeks)

+ How do you apply oral gel?

We recommend you use our oral gel twice daily, after flossing and brushing, as part of your oral care routine. Squeeze a pea-sized amount of the oral gel onto a clean fingertip, cotton swab, or soft toothbrush, then apply the gel to the outside and inside of your upper and lower gums. Allow the gel to dissolve, and spit out any excess. Do not swallow the gel, and avoid eating or drinking for the next 30 minutes. The gel can also be applied to your tongue or the roof of your mouth.

What are the key ingredients in your dental gel?

Our patented blend of the antioxidants Phloretin and Ferulic Acid works in harmony with your mouth's natural defenses to help calm and revitalize your gums and mouth's soft tissue. You'll also get the benefit of Xylitol, a naturally-derived ingredient that goes straight to the source of decay. It works by actively blocking and "starving" the harmful bacteria most responsible for forming cavities.

When should I apply the dental gel, before or after brushing and rinsing?

Apply a pea-sized amount to both your upper and lower gums in the morning and evening after brushing your teeth and rinsing. For best results, do not eat or drink for 30 minutes after applying AO ProVantage Gel.

Is this safe for use after dental implants, whitening, or orthodontic procedures?

Our dental gel for gums is specifically designed to soothe soft tissue in the oral cavity. The inclusion of powerful antioxidants and soothing essential oils (like Sage and Clove Flower) makes it beneficial for use when gums or soft tissues are irritated. This dental gel can also be used on the tongue for an overall soothing effect.

Is there a difference between AO ProVantage Gel and On-the-Go AO ProVantage Dental Gel?

The formula is the same, the only difference is the size. AO Provantage Gel is 30 ml, and the On-the-Go option is 15 ml.

What does your gum gel do?

The AO ProVantage Dental Gel is a highly concentrated, aqueous gel designed specifically to be applied directly to the soft tissues of your mouth (gums, lips, palate, and cheeks). Its primary purpose is to provide soothing comfort and a healthier oral environment. It supports your mouth's natural defenses by delivering a patented blend of antioxidants, essential oils, and Xylitol. Think relief from mouth burn, dry mouth, irritation from braces, dental implant irritation, post-surgery and post-teeth whitening sensitivity, and more.

Does oral gel help with inflamed gums?

Yes, absolutely. This is one of the main reasons the AO ProVantage Dental Gel is highly recommended by periodontists. The "AO" stands for Antioxidant, and these topically applied antioxidants are known for their anti-inflammatory effects. When applied to the gums, the cool and minty gel instantly soothes irritation, reduces the appearance of inflammation, and promotes the healing of damaged oral tissues.