Tube of sensitive toothpaste with a smear and a flower on white background.

The toothpaste dentists recommend for seriously sensitive teeth

Tooth sensitivity keeping you from eating, drinking, and doing the things you love? Try AO ProToothpaste Sensitive, a specially formulated toothpaste packed with antioxidants and clinically proven to reduce sensitivity.

Trusted and recommended by 2600+ dentists

Specially formulated to provide lasting relief

What the experts say

"We get remarkable results within 72 hours of patient use [...] a quality solution to tooth sensitivity."

Portrait of a smiling older man in a suit, with a circular frame.

Dr Sam Low


Specialist Periodontist

Gainesville, Florida

"[For] challenging cases, my go-to recommendation is PerioSciences Toothpaste for Sensitive Teeth."

Gretchen Estep


Registered Dental


Plano, Texas

Smiling woman with blond hair outdoors.

Soothing ingredients

The natural antioxidants Phloretin and Ferulic Acid neutralize free radicals to help promote overall oral health.

A product box for PerioSciences AO ProToothpaste Sensitive with visible label and drug facts.
Alt-text: A sprig of blue forget-me-not flowers resting on a pile of white granules.

Potassium Nitrate combats sensitivity and Allantoin, found in many plants, soothes and reduces feelings of discomfort.

Click on each ingredient to learn more

We've worked with the dentist community for over a decade to develop AO ProToothpaste for Sensitive Teeth.

What makes it so special is its unique combination of trusted ingredients with naturally sourced antioxidants - to soothe sensitivity and gently clean and strengthen teeth.

AO ProToothpaste for Sensitive Teeth was used in a published clinical study and patients in the study reported relief from sensitivity within 72 hours.

Not sure our toothpaste is right for you? Ask your dentist if they trust and recommend our ingredients.

The natural antioxidants Phloretin, Ferulic Acid, and Silymarin combine to neutralize free radicals from peroxide, nicotine, alcohol, and metals - amplifying oral health.

Helping people discover their best smile

Clinically proven relief

within 72 hours

Recommended by
2600+ dentists

Formulated for

long-lasting relief



Made in the USA



Lasts 60 days

$0.16 per use


Toothpastes for every need

Toothpaste tube with natural green powder and a beige smear of toothpaste.


Clean your mouth with 100% natural ingredients.

Toothpaste tube with squeezed-out content and golden droplets on white background.


Perfect for those looking to lock in moisture in the mouth.

Toothpaste tube with clover flower and smear of toothpaste on a white background.


Soothe sensitivity in the mouth.

Toothpaste tube with a smear of toothpaste and a sliced orange with leaves.

White Care

Maintain a brighter, whiter smile.

Frequently Asked Questions

Does AO ProToothpaste for Sensitive Teeth contain fluoride?

How long will each tube of AO ProToothpaste for Sensitive Teeth last?

Can I use AO ProToothpaste for Sensitive Teeth every day?